Achieve Life Sciences, Inc..
ACHV.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products
Achieve Life Sciences, Inc. is a pharmaceutical company dedicated to developing and commercializing cytisinicline for smoking cessation and nicotine dependence. Cytisinicline is a plant-based alkaloid with a high binding affinity to the nicotinic acetylcholine receptor. Achieve Life Sciences is focu...Show More
Better Health for All
60
Achieve Life Sciences' core product, cytisinicline, is a treatment for nicotine dependence for smoking and e-cigarette cessation.
1
This product directly addresses a major global health issue, as tobacco use is responsible for over eight million deaths worldwide and nearly half a million in the US annually, with associated healthcare costs exceeding $600 billion.
2
The company's entire portfolio is dedicated to this health-positive solution, resulting in no revenue from harmful products. The company's R&D expenses for the nine months ended September 30, 2025, were $19.124 million out of total operating expenses of $40.1 million, representing approximately 47.69% of operating expenses dedicated to health improvement.
3
The company's operations generate significant positive health externalities by aiming to reduce the widespread harms of nicotine addiction. Cytisinicline is being developed as a preventative health measure, focusing on cessation to avert smoking-related diseases.
4
The company's sole mission is to mitigate nicotine addiction.
5
Clinical trials for cytisinicline, including ORCA-3, were randomized and placebo-controlled, with all subjects receiving behavioral support.
6
The ORCA-OL trial was open-label and conducted at 29 sites across the US.
7
Fair Money & Economic Opportunity
0
Achieve Life Sciences, Inc. is a pharmaceutical company focused on developing and commercializing cytisinicline for smoking cessation.
1
The provided articles and company description indicate that its core business does not involve lending, insuring, moving, or storing money, nor does it offer financial products or services to consumers. Therefore, all Key Performance Indicators (KPIs) under the 'Fair Money & Economic Opportunity' value, which are designed to assess financial institutions, are not applicable to this company. No evidence was found in the articles to score any of these financial services-specific KPIs, leading to their omission as per the scoring rules.
Fair Pay & Worker Respect
0
No quantitative data is available across the provided articles to assess Achieve Life Sciences (ACHV.US) against the specified Fair Pay & Worker Respect KPIs.
1
Employee reviews offer qualitative insights into compensation, work-life balance, management, and culture, but lack specific numbers or outcomes required for scoring.
2
Data provided for other companies or general industry surveys are not applicable to ACHV.US.
Fair Trade & Ethical Sourcing
0
No specific, concrete data points were found in the provided articles to assess Achieve Life Sciences, Inc. against any of the Fair Trade & Ethical Sourcing KPIs. The articles mention an exclusive supply agreement for Cytisine API and finished tablets, indicating a supply chain, but offer no details regarding fair-trade certifications, audit frequency, labour incidents, traceability, remediation speed, ethical clauses in contracts, materials risk, or supplier diversity spend.
1
Honest & Fair Business
0
No specific, concrete data points were found in the provided articles to assess Achieve Life Sciences, Inc. against the defined KPIs for Honest & Fair Business. While governance documents such as a Whistleblower Policy and a Code of Business Conduct & Ethics are listed,
1
the articles do not provide any details regarding their strength, enforcement, effectiveness, or any associated quantitative metrics required by the rubric.
Kind to Animals
0
No specific, concrete evidence was found in the provided articles regarding Achieve Life Sciences, Inc.'s performance on any of the 'Kind to Animals' KPIs. The articles discuss general industry trends, regulatory changes by the FDA, and actions by other companies, but do not provide any data directly attributable to ACHV.US concerning cruelty-free certifications, alternative testing methods, humane certifications, wildlife conservation, ethical input substitution, supplier audits, cage-free sourcing, animal testing policies, animal testing volume, innovation investment, animal agriculture ethics, animal-free R&D collaboration, or public policy engagement.
No War, No Weapons
0
Achieve Life Sciences, Inc. is a pharmaceutical company focused on developing and commercializing cytisinicline for smoking cessation and nicotine dependence. The provided articles indicate that the company's core business activities do not involve arms, defense, or dual-use technologies. There is no evidence of revenue from arms or defense contracts, R&D investment in dual-use technologies, or sales to embargoed regimes.
1
The company does not have defense-related business activities requiring board oversight, export certifications, or defense-related lobbying.
2
Furthermore, there is no evidence of involvement in surveillance, controversial weapons, or procurement from conflict zones.
3
The company's operations do not necessitate war-risk audits, conflict-partner reviews, or ethical red lines related to weapons.
4
Planet-Friendly Business
0
No evidence available to assess Achieve Life Sciences, Inc. on Planet-Friendly Business.
Respect for Cultures & Communities
0
Achieve Life Sciences established 3 formal partnership agreements with the University of Auckland, Health Economics Research Group (HERG) at Brunel University London, and Lakes District Health Board.
1
These partnerships were for the RAUORA study, which focused on indigenous New Zealanders (Māori) and their extended family.
2
Out of 1,105 Māori or whānau who expressed interest in participating in the study, 679 were randomized, resulting in a 61.45% participation rate of affected communities in the FPIC process.
3
Safe & Smart Tech
0
No specific evidence regarding Achieve Life Sciences, Inc. (ACHV.US) was found in the provided articles for any of the Safe & Smart Tech KPIs.
1
The articles either discuss general trends and risks within the broader life sciences industry, present hypothetical case studies, or refer to a different entity named 'Achieved Compliance', which is not ACHV.US.
2
Therefore, no KPIs can be scored based on the provided information.
Zero Waste & Sustainable Products
0
The provided articles discuss general sustainability efforts and waste reduction initiatives within the life sciences industry, often referencing larger pharmaceutical companies or recruitment firms. However, there is no specific, quantifiable evidence directly attributable to ACHV.US regarding its waste diversion rates, product recyclability, packaging sustainability, recycled content, single-use plastic reduction, take-back programs, circular design principles, waste reduction initiatives, hazardous waste management, product durability, repairability score, waste audit frequency, zero waste certification, waste disposal violations, material efficiency, packaging-to-product ratio, waste reduction targets, supplier waste requirements, or customer waste education.
1
Therefore, no KPIs can be scored for ACHV.US based on the given information.