MASHINIi

Assembly Biosciences, Inc..

ASMB.US | Research and experimental development on natural sciences and engineering

Assembly Biosciences, Inc. is a biotechnology company focused on the development of novel therapeutics targeting hepatitis B virus (HBV) infection and other viral diseases. The company's core focus is on advancing a portfolio of core protein allosteric modulators (CpAMs) designed to disrupt HBV repl...Show More

Ethical Profile

Mixed.

Assembly Biosciences is dedicated to developing antiviral therapies for diseases like Hepatitis B, Hepatitis D, and Herpes, affecting millions globally. Their pipeline includes novel treatments like ABI-6250 and ABI-4334 in clinical trials, supported by a partnership with Gilead Sciences. The company demonstrates ethical commitment through GCP compliance, comprehensive employee benefits including mental health support, a robust whistleblower policy, and anti-corruption training. It also scores 75-80 on transparency. Critics point to the inherent use of animal testing in preclinical drug development, a common practice in the biotech sector. While a sustainability program exists, specific quantitative environmental data is not publicly available.

Value Scores

Better Health for All20
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect40
-100100
Fair Trade & Ethical Sourcing-20
-100100
Honest & Fair Business20
-100100
Kind to Animals-30
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products-50
-100100

Better Health for All

20

Assembly Biosciences is a biotechnology company focused entirely on the research and development of novel therapeutics for serious viral diseases, including chronic hepatitis B and D, and herpesviruses.

1
These diseases affect millions globally and cause significant mortality.
2
The company does not manufacture or distribute products, focusing solely on R&D, therefore it has no revenue from products with negative health outcomes, and pricing/accessibility data are not applicable.
3
While the company received a $100 million upfront payment from a partnership,
4
there is no specific data on the percentage of Assembly Biosciences' *own* R&D budget allocated to health improvement. The company adheres to Good Clinical Practice (GCP) standards, including informed consent procedures and animal welfare, and conducts randomized, blinded, and placebo-controlled clinical trials.
5
It also offers comprehensive employee benefits, including mental health and wellness programs and an employee assistance program.
6

Fair Money & Economic Opportunity

0

No evidence available to assess Assembly Biosciences, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

40

Assembly Biosciences provides 100% company-covered medical, dental, and vision insurance for employees and their families, with benefits generally effective on the date of hire.

1
Employee engagement, as indicated by an average Glassdoor rating of 4.1 out of 5 stars (82%) based on 18 reviews, shows 76% of employees would recommend working there and 83% approve of the CEO.
2
There is no public record of substantiated labor-law or human-rights violations in the past three years.
3

Fair Trade & Ethical Sourcing

-20

Assembly Biosciences, Inc. focuses solely on research and development and does not manufacture or distribute products, therefore it does not procure or trade physical commodities that would typically require fair-trade certifications. The company conducts supplier audits at least annually through a third-party compliance partner.

1

Honest & Fair Business

20

Assembly Bio has a formal Whistleblowing and Whistleblower Protection Policy, which includes a 24/7 anonymous hotline available to employees, contractors, and third parties, managed by a third-party service provider.

1
The company explicitly prohibits retaliation against those who report violations in good faith, and allegations of retaliation are promptly investigated.
2
The company reported zero financial restatements for the fiscal year ended December 31, 2024, and indicated no error corrections requiring a recovery analysis of incentive-based compensation.
3
All new employees receive training on anti-bribery and anti-corruption.
4
A globally recognized third-party partner provides external assurance of compliance with ethical standards at least once a year.
5
The company's Form 10-K filing from March 2025 states that Gilead has the right to designate two directors to the company's board of directors.
6

Kind to Animals

-30

Assembly Biosciences is a biotechnology company focused on research and development, not manufacturing or distributing products. Therefore, KPIs related to product certification, animal agriculture, or animal-derived ingredients are not applicable. The company conducts nonclinical studies, including in vitro and animal studies, for regulatory filings and toxicology, explicitly mentioning studies in non-human primates and GLP toxicology for multiple compounds.

1
While its policy requires contract research organizations (CROs) to have Institutional Animal Care and Use Committees (IACUC) and practice the 3Rs (Replacement, Reduction, and Refinement), indicating an intent to use non-animal systems whenever possible and minimize animal use, traditional animal assays dominate, particularly where legally mandated for safety profiles.
2
No specific data on the percentage of non-animal methods used or the number of animals used annually is provided, but extensive nonclinical studies are required.
3
The company's R&D expenses for the nine months ended September 30, 2025, were $47.6 million, but there is no explicit mention of the percentage of this budget allocated to animal-free technologies.
4
There is no evidence of participation in multi-stakeholder initiatives for animal-free standards or active engagement in animal welfare policy improvement beyond complying with regulations.

No War, No Weapons

0

No evidence available to assess Assembly Biosciences, Inc. on No War, No Weapons.

Planet-Friendly Business

0

Assembly Biosciences, Inc. does not provide specific, quantifiable data for any of the Planet-Friendly Business KPIs in the provided articles. While the company states commitments to environmental, health, and safety (EHS) policies, energy efficiency (e.g., energy-efficient lighting), and resource conservation (e.g., composting and recycling programs), these are general statements of intent or actions without measurable outcomes or percentages that align with the rubric's quantitative thresholds.

1
External ratings or scores, such as a 'Reduced Green House Gas Emissions: 38.4 score' from a third-party, are not considered company-reported facts for scoring purposes.
2
Therefore, no KPIs can be scored based on the available evidence.

Respect for Cultures & Communities

0

No evidence available to assess Assembly Biosciences, Inc. on Respect for Cultures & Communities.

Safe & Smart Tech

0

No evidence available to assess Assembly Biosciences, Inc. on Safe & Smart Tech.

Zero Waste & Sustainable Products

-50

Assembly Biosciences has implemented energy-efficient lighting in its offices and encourages composting and recycling programs.

1
The company maintains a Chemical Hygiene Plan (CHP) that outlines procedures for hazardous chemical use, storage, monitoring, protective equipment, and disposal, with the CEO responsible for chemical hygiene.
2
The company states compliance with all relevant laws, rules, regulations, and corporate policies.
3

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.