MASHINIi

Klotho Neurosciences, Inc..

KLTO.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Klotho Neurosciences, Inc. is a biopharmaceutical company focused on the discovery and development of novel therapeutics for neurodegenerative and neurodevelopmental disorders. The company's research and development efforts are centered on leveraging the Klotho protein, which plays a crucial role in...Show More

Ethical Profile

Mixed.

Klotho Neurosciences (KLTO.US) presents a mixed ethical profile. The company is developing gene therapies for neurodegenerative diseases like Alzheimer's and ALS, with pre-clinical trials reportedly showing a 20% increase in lifespan in mice. KLTO-202 has secured FDA Orphan Drug Designation for ALS, highlighting its potential. However, as an early-stage biotech, its development inherently involves animal testing, which critics point to as a conflict with animal welfare values. Reports also suggest recent Nasdaq compliance issues warrant monitoring. Information on fair pay, environmental impact, and business transparency is currently insufficient to form a comprehensive assessment.

Value Scores

Better Health for All-10
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals-70
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

-10

Klotho Neurosciences' entire business is devoted to developing disease-modifying therapies for universally fatal neurodegenerative and age-related disorders.

1
Pre-clinical trials have shown a 20% increase in lifespan in mice, indicating revolutionary health benefits in early-stage research.
2
The company currently has no revenue, meaning it has no revenue from products with negative health impacts.
3
However, Klotho holds exclusive patents in the USA, Europe, and China for its secreted splice variant, with no specific information provided on patent policies in low-income countries, suggesting inflexible enforcement.
4
The company plans to conduct randomized, placebo-controlled trials for its therapies, but there is no information on ethical conduct or diversity in trial populations, indicating basic ethical standards with some gaps.
5

Fair Money & Economic Opportunity

0

No evidence available to assess Klotho Neurosciences, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

No specific, concrete data points were found across the provided articles to assess Klotho Neurosciences, Inc. against any of the Fair Pay & Worker Respect KPIs.

1
All articles explicitly state that they contain placeholder content and lack relevant quantitative data, regulatory actions, certifications, or comparisons for KLTO.US.
2

Fair Trade & Ethical Sourcing

0

No information relevant to Klotho Neurosciences, Inc.'s fair trade and ethical sourcing practices, supply chain, audits, incidents, traceability, remediation, contractual clauses, materials risk, or supplier diversity was found in the provided articles.

1

Honest & Fair Business

0

No specific, quantifiable evidence was found in the provided articles for any of the 'Honest & Fair Business' KPIs for Klotho Neurosciences, Inc. (KLTO.US). While articles mention Nasdaq compliance issues, including delisting notices and compliance extensions, and a change of accounting firm, these do not provide the concrete data points required by the rubric's quantitative thresholds for regulatory fines, financial restatements, or audit coverage percentage.

1
Information regarding whistleblower policies, transparency indices, ESG controversies, complaint resolution times, board independence, anti-corruption policies, or third-party verification for KLTO.US was not available.
2

Kind to Animals

-70

Klotho Neurosciences, Inc. conducts animal studies in mouse and non-human primate models for preclinical research and will complete FDA-mandated animal safety studies.

1
The company has supported these studies over the past two years, including "proof of concept" studies in two animal models of human ALS.
2
There is no evidence of a formal policy to reduce or prohibit animal testing, nor any mention of using alternative methods or seeking to phase out animal use. The company's R&D activities involve animal models, but there is no specific information on the percentage of the R&D budget invested in animal-free technologies.
3
The use of animal models for drug development, without any stated commitment to alternatives or reduction, indicates a reliance on traditional animal testing methods.

No War, No Weapons

0

Klotho Neurosciences, Inc. is a biopharmaceutical company focused on the discovery and development of gene therapies for neurodegenerative diseases such as ALS, Alzheimer's, and Parkinson's.

1
Its core business activities, including R&D and product pipeline, are centered on these medical applications. The company is not involved in arms or defense contracts, dual-use technologies, or military sales.
2
There is no evidence of any defense-related lobbying, procurement, or operations in conflict zones.
3
All available information indicates that the company's business model is entirely unrelated to the arms industry or conflict facilitation.

Planet-Friendly Business

0

No specific data regarding KLTO.US's environmental performance or planet-friendly business practices was found in the provided article.

1
The article explicitly states that it contains no information relevant to KLTO.US or the Planet-Friendly Business value, making it impossible to extract any relevant data for scoring.
2

Respect for Cultures & Communities

0

No evidence available to assess Klotho Neurosciences, Inc. on Respect for Cultures & Communities.

Safe & Smart Tech

0

No evidence available to assess Klotho Neurosciences, Inc. on Safe & Smart Tech.

Zero Waste & Sustainable Products

0

No evidence available to assess Klotho Neurosciences, Inc. on Zero Waste & Sustainable Products.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.