LENZ Therapeutics, Inc..
LENZ.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products
LENZ Therapeutics, Inc. is a late-stage clinical biopharmaceutical company focused on developing and commercializing innovative, preservative-free, single-use ophthalmic pharmaceutical products that improve vision and quality of life. Their primary focus is on addressing presbyopia, also known as ag...Show More
Better Health for All
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LENZ Therapeutics' core business is the development and commercialization of VIZZ (aceclidine ophthalmic solution), an FDA-approved, once-daily eye drop for presbyopia.
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This product restores clear near vision for up to 10 hours, with clinical trials showing 53% of patients achieving 3 or more lines of reading improvement and 81% achieving 2 or more lines within 30 minutes.
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Presbyopia affects an estimated 1.8 billion people globally.
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The company's sole product, VIZZ, is an FDA-approved treatment, and there is no evidence of revenue generated from products or activities with well-established negative health outcomes.
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The company received $30 million in PIPE financing in July 2024 and $47 million in Series A financing in June 2021, intended to support regulatory, pre-commercial, and potential commercial launch activities, but a specific percentage of R&D or capital allocation for health improvement is not provided.
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The product treats an age-related condition rather than preventing it.
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Full Prescribing Information is available, but there is no specific data on health data protection practices.
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The company conducted a 58-patient Phase II trial, and aceclidine was well tolerated with no serious adverse events, and the majority of adverse reactions were mild, transient, and self-resolving.
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Fair Money & Economic Opportunity
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No evidence available to assess LENZ Therapeutics, Inc. on Fair Money & Economic Opportunity.
Fair Pay & Worker Respect
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No evidence available to assess LENZ Therapeutics, Inc. on Fair Pay & Worker Respect.
Fair Trade & Ethical Sourcing
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No information regarding fair trade certifications, audit frequency, forced or child labor incidents, supply chain traceability, remediation speed, ethical clauses in contracts, high-risk materials, or supplier diversity spend was found in the provided articles.
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The articles primarily focus on financial reporting, corporate governance, and compliance with healthcare professional interaction regulations, not supply chain ethics.
Honest & Fair Business
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LENZ Therapeutics has a whistleblower policy that allows individuals to anonymously report activities that violate the policy by emailing the Compliance Officer.
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The audit committee is responsible for adopting and overseeing procedures to address complaints regarding accounting, internal accounting controls, and auditing matters, including confidential, anonymous submissions by employees.
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The company's Insider Trading Policy explicitly states that it does not limit protected activities set forth in the Whistleblower Policy, and the policy applies to individuals both inside and outside the United States.
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Six of the seven directors on the board are determined to be independent, representing approximately 85.7% of the board.
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The company has a comprehensive compliance program based on OIG Guidance and AdvaMed Code, which includes policies governing interactions with healthcare professionals and scientific/educational activities.
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The company declares compliance with California Health & Safety Code §§ 119400-119402 and is subject to the U.S. Foreign Corrupt Practices Act (FCPA) or comparable foreign regulations.
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The company relies on third parties for the production of clinical and commercial quantities of its products, and all Contract Manufacturing Organizations (CMOs), including analytical and distribution chain partners, have been inspected by the FDA for compliance with current Good Manufacturing Practices (cGMP) regulatory guidelines.
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Kind to Animals
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No specific, concrete evidence regarding LENZ.US's animal welfare practices, animal testing policies, use of alternatives, sourcing, or conservation initiatives was found in the provided articles. The fact that LENZ.US is not listed in an article identifying companies that exploit animals is an absence of negative evidence, but it does not provide specific, measurable data points to score any KPI against the rubric's quantitative thresholds.
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No War, No Weapons
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LENZ Therapeutics, Inc. is a biopharmaceutical company focused on developing and commercializing ophthalmic pharmaceutical products for presbyopia.
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The provided articles consistently state that the company's core business is not involved in arms or defense contracts, dual-use technology, or sales to embargoed regimes.
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There is no mention of any activities related to the military, conflict facilitation, or peacebuilding initiatives.
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Consequently, all KPIs related to 'No War, No Weapons' are deemed 'Not applicable' to the company's core operations or business model based on the available evidence.
Planet-Friendly Business
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The provided articles, which are primarily SEC filings (Form 10-Q, Form 10-K, and Prospectus), focus on financial performance, clinical trial results, and general business risks. Multiple articles explicitly state a 'Lack of specific data on environmental, social, and governance (ESG) metrics' or 'Lack of detailed information on specific environmental, health, and safety metrics.'
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Consequently, there is no evidence within the provided materials to assess LENZ.US against any of the 'Planet-Friendly Business' KPIs, such as carbon emissions, renewable energy use, water consumption, waste diversion, or climate-related policies and initiatives.
Respect for Cultures & Communities
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No evidence available to assess LENZ Therapeutics, Inc. on Respect for Cultures & Communities.
Safe & Smart Tech
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No specific, concrete data points relevant to LENZ.US or the 'Safe & Smart Tech' ethical value were found in the provided article. The article discusses general FDA guidance on electronic records and signatures (21 CFR Part 11) but does not contain information about LENZ.US's performance on any of the assessed KPIs.
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Zero Waste & Sustainable Products
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No specific data related to LENZ.US or its products regarding waste diversion rates, product recyclability, packaging sustainability, recycled content, single-use plastic reduction, take-back programs, circular design principles, waste reduction initiatives, hazardous waste management, product durability, repairability, waste audit frequency, zero waste certification, waste disposal violations, material efficiency, packaging-to-product ratio, waste reduction targets, supplier waste requirements, or customer waste education was found in the provided article.
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The article focuses on general pharmaceutical waste management without company-specific details.
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