MASHINIi

Moleculin Biotech, Inc..

MBRX.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Moleculin Biotech, Inc. is a biopharmaceutical company focused on the development of therapies for hard-to-treat cancers and viruses. Their pipeline includes preclinical and clinical-stage drug candidates targeting various cancer types, including drug-resistant tumors, as well as potential antiviral...Show More

Ethical Profile

Mixed.

Moleculin Biotech, Inc. (MBRX.US) focuses on developing therapies for serious diseases, with lead drug Annamycin showing a 59.4% clinical benefit rate and 13.5 months median overall survival in trials for soft tissue sarcoma lung metastases. It holds FDA/EMA Fast Track and Orphan Drug status for acute myeloid leukemia. However, as a pharmaceutical developer, its business model inherently relies on animal testing, which critics point to as fundamentally conflicting with animal welfare. While the company maintains a Code of Business Conduct and an Ethics Hotline, detailed data on other ethical areas like fair pay, ethical sourcing, or environmental impact is largely unavailable.

Value Scores

Better Health for All-20
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business-30
-100100
Kind to Animals0
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

-20

Moleculin Biotech's entire business is devoted to developing therapies for hard-to-treat cancers and pathogenic viruses, with all products aiming to provide substantial health benefits, including Annamycin for AML and STS, WP1066 for brain tumors, and WP1122 for viruses.

1
Annamycin has demonstrated no cardiotoxicity in 90 subjects across five clinical trials, even at doses exceeding the FDA's lifetime maximum, which is a significant safety improvement over existing anthracyclines.
2
However, two adverse events (allergic reactions) were reported in one AML trial, and two subjects experienced asymptomatic adverse events meeting stoppage criteria in a WP1122 Phase 1a trial.
3
The company offers expanded access to investigational products for patients with serious or life-threatening diseases when other options are exhausted, and the MIRACLE trial is global, including sites in the US, Europe, and the Middle East.
4
However, the company is not currently prioritizing the development of WP1096 for antivirals over oncology initiatives.
5
The company's risk transparency includes forward-looking statements and mentions risks detailed in SEC filings, but does not provide comprehensive public data resources for all health claims.
6
The MIRACLE trial is a randomized, double-blind, placebo-controlled study, registered on clinicaltrials.gov and euclinicaltrials.eu, and includes an adaptive design for dose optimization.
7
The company holds composition of matter patent protection for Annamycin until 2040, with potential extension to 2045, but no information on patent flexibility for global health needs is provided.
8
The company's operations generate positive health externalities by developing a drug (Annamycin) designed to lack cardiotoxicity, addressing the issue that nearly half of all cancers are treated with cardiotoxic anthracyclines.
9

Fair Money & Economic Opportunity

0

No evidence available to assess Moleculin Biotech, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

Moleculin Biotech, Inc. had 17 employees as of December 31, 2024.

1
While CEO total compensation for 2024 was reported as $1,458,759,
2
there is no data on median employee compensation, preventing the calculation of a CEO-median pay ratio. No specific, quantitative data was provided in the articles for any other Fair Pay & Worker Respect KPIs, including living wage coverage, collective bargaining share, safety incident rate, pay equity ratio, worker engagement score, voluntary turnover rate, labor violation incidents, insecure contract share, or health insurance coverage. Therefore, no KPIs can be scored.

Fair Trade & Ethical Sourcing

0

No specific, concrete evidence regarding fair trade certifications, audit frequency, forced or child labor incidents, traceability coverage, remediation speed, ethical clause coverage, materials risk index, or supplier diversity spend was found in the provided article.

1
The article is identified as a code of conduct and does not contain data on actual ethical sourcing practices.
2

Honest & Fair Business

-30

Moleculin Biotech, Inc. provides an Ethics Hotline, Fax Number, and Email Address for anonymous reporting, but there is no evidence of independent investigation processes.

1
The company's board of directors has 5 out of 6 members identified as independent under Nasdaq Rules, which equates to approximately 83.33% conflict-free directors.
2
An anti-corruption policy is in place, prohibiting gifts or benefits of significant value (defined as over $500) without pre-approval, but the available evidence does not provide clear guidance on facilitation payments or comprehensive gift thresholds.
3

Kind to Animals

0

No evidence available to assess Moleculin Biotech, Inc. on Kind to Animals.

No War, No Weapons

0

Moleculin Biotech, Inc. is a Phase 3 clinical stage pharmaceutical company focused on developing therapeutic candidates for hard-to-treat tumors and viruses, including acute myeloid leukemia, soft tissue sarcoma lung metastases, brain tumors, pancreatic cancer, and other viral indications.

1
The provided articles describe the company's drug development programs and corporate information. No evidence is available in the articles regarding the company's involvement in arms manufacturing, military contracts, dual-use technologies, sales to embargoed regimes, peacebuilding investments, or any other activities related to the 'No War, No Weapons' value. Therefore, no KPIs can be scored based on the provided information.

Planet-Friendly Business

0

No specific sustainability data is available for Moleculin Biotech, Inc. across any of the assessed Planet-Friendly Business KPIs.

1
The provided articles indicate a complete absence of quantitative sustainability data, regulatory actions, violations, fines, compliance issues, certifications, awards, or recognitions related to environmental performance.
2

Respect for Cultures & Communities

0

No evidence available to assess Moleculin Biotech, Inc. on Respect for Cultures & Communities.

Safe & Smart Tech

0

The company's privacy policy states it collects only personal information voluntarily provided by users, indicating a commitment to limiting data collection.

1
It also notes the use of cookies with unique identifiers and IP addresses for aggregate reporting and website improvement.
2
Personal data may be transferred to third parties for processing in connection with the company's business, consistent with the original collection purposes.
3

Zero Waste & Sustainable Products

0

No specific, concrete data points or initiatives related to waste management, product recyclability, packaging sustainability, or other zero waste and sustainable product metrics for MBRX.US were found in the provided articles.

1
Several articles explicitly state that sustainability data for MBRX.US is currently unavailable, or that no information is available regarding regulatory actions, violations, fines, or compliance issues.
2
Therefore, no KPIs can be scored based on the provided evidence.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.