Fair Pay & Worker Respect

In Fiscal Year 2024, the CEO pay ratio was 20:1.

Employee reviews on Glassdoor indicate an average worker engagement score of 3.6 out of 5 stars. The company underwent a significant reorganization in May 2018, which included a workforce reduction of nearly 60%. In 2018, a corporate objective was to achieve a voluntary turnover rate of ≤7.5%. However, in 2025, Prothena is laying off 63% of its workforce, which entered 2025 with 163 employees. This follows a separate wave of layoffs in 2018, and reviews also mention high turnover in some periods.

Honest & Fair Business

Prothena Corporation plc has an Open Door Policy for Reporting Suspected Violations and Complaints, which includes procedures for confidential, anonymous submissions regarding accounting or auditing matters.

This policy applies to all employees, officers, and directors across the company and its subsidiaries, with the Audit Committee responsible for supervising and overseeing inquiries and investigations. The company has an anti-corruption policy, and its Code of Conduct requires annual acknowledgment, but details on training frequency or effectiveness metrics are not provided. The Audit Committee is required to have a minimum of three members, all of whom must be independent directors as defined by Nasdaq Listing Rules. Executive officers, directors, and other designated employees must furnish annual written disclosures of affiliations and potential conflicts of interest. The company has not had any financial restatements in the past five years, as evidenced by the availability of financial statements without mention of restatements and the Code of Conduct emphasizing full, fair, accurate, timely, and understandable disclosure.

No War, No Weapons

Prothena Corporation plc is a clinical-stage biotechnology company focused on the discovery and development of novel therapies for neurodegenerative and rare peripheral amyloid diseases.

The company's 2024 report explicitly states no information was found regarding its involvement in arms contracts or peacebuilding initiatives. No evidence suggests the company develops or sells dual-use products, has defense-related business activities, or has exposure to any weapons.

Safe & Smart Tech

The company experienced a data breach between December 20, 2021, and April 22, 2022, which was announced in June/July 2022.

This incident involved unauthorized access to an employee's email account, exposing sensitive consumer information including names, addresses, Social Security numbers, or tax identification numbers. A cybersecurity forensic firm was engaged to investigate the incident, and data breach letters were sent to affected individuals on June 2, 2022. The unauthorized party was believed to be attempting to gather information to commit wire fraud against the company.