MASHINIi

Scholar Rock Holding Corporation.

SRRK.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Scholar Rock Holding Corporation is a biopharmaceutical company focused on the discovery and development of innovative medicines for the treatment of serious diseases in which signaling by protein growth factors plays a crucial role. The company's pipeline includes product candidates targeting disea...Show More

Ethical Profile

Mixed.

Scholar Rock (SRRK.US) aims to improve "Better Health for All" by developing treatments for serious diseases such as spinal muscular atrophy and certain cancers. However, its ethical standing is mixed. Reports indicate the CEO's compensation nearly doubled to $8 million in 2024, though the CEO-to-median-employee pay ratio is not publicly available. Employee sentiment on Glassdoor averages 3.9/5. As a biopharmaceutical company, its drug development likely involves animal testing, which critics point to as conflicting with "Kind to Animals." Specific environmental metrics are largely unavailable, despite a reported "net impact ratio" of 66.0%. Many other ethical areas lack sufficient public data for a comprehensive assessment.

Value Scores

Better Health for All50
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect10
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals0
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

50

Scholar Rock Holding Corporation is entirely focused on developing investigational therapies for serious diseases with unmet needs, including Spinal Muscular Atrophy (SMA), cancer, fibrosis, rare neuromuscular diseases, and iron-restricted anemia.

1
Their pipeline is dedicated to providing substantial health benefits, with apitegromab, a muscle-targeted treatment for SMA, demonstrating clinical success in a pivotal Phase 3 trial.
2
The company has no revenue from products with negative health outcomes. The FDA's Complete Response Letter for apitegromab was due to issues at a third-party manufacturing facility, not concerns regarding the drug's safety data, indicating an outstanding safety record for the product itself.
3
Scholar Rock has an active Expanded Access Program (EAP) in the US for eligible SMA patients and designs inclusive clinical trials consistent with regulatory guidance.
4
The company discloses regulatory communications, such as the FDA's CRL, and provides information about investigational products.
5
Their entire business model is dedicated to turning scientific discoveries into a pipeline of investigational therapies, reflecting a >25% R&D budget for health improvement. The company's goal is to provide access to investigational therapies at the appropriate time and in the correct manner for patients, and they anticipate exploring access in countries beyond the US and Europe.
6
However, there is no specific evidence regarding their approach to patents in relation to global health needs.

Fair Money & Economic Opportunity

0

Scholar Rock Holding Corporation is a biopharmaceutical company focused on developing and commercializing medicines, not a financial institution.

1
The company does not offer lending, deposit, or other financial services to consumers.
2
Therefore, all KPIs related to financial services, such as underserved client share, pricing fairness, exploitative fee exposure, inclusion initiatives, data accessibility for financial data, fair lending compliance, wealth building outcomes, financial literacy initiatives, debt burden ratio, geographic inclusion for banking services, and product simplicity for financial products, are not applicable to its core business model. While the company aims to deliver novel therapies to underserved patients, this relates to medical treatment, not financial inclusion or economic opportunity as defined by the rubric.
3

Fair Pay & Worker Respect

10

Scholar Rock's employee engagement is reflected in Glassdoor ratings, with an overall employee rating of 3.9 out of 5 stars.

1
Approximately 78% of employees would recommend working at the company, and 77% rate the business outlook positively.
2
The company offers a 401(k) plan with a 50% match on employee contributions up to 6% of base salary.
3
Full-time employees are eligible for medical, disability, and life insurance programs, with the company paying premiums for term life insurance and long-term disability.
4

Fair Trade & Ethical Sourcing

0

No evidence available to assess Scholar Rock Holding Corporation on Fair Trade & Ethical Sourcing.

Honest & Fair Business

0

No specific, quantifiable data points were found in the provided articles for any of the 'Honest & Fair Business' KPIs, such as regulatory fines, transparency index scores, financial restatements, or details on whistleblower and anti-corruption policies.

1
While a Complete Response Letter (CRL) was received in September 2025 regarding observations at a third-party fill-finish facility, which was classified as 'official action indicated' (OAI), no associated fine amounts were disclosed.
2

Kind to Animals

0

No specific, concrete evidence was found in the provided articles to assess Scholar Rock Holding Corporation (SRRK.US) against any of the 'Kind to Animals' KPIs. Article

1
pertains to Keros Therapeutics, Inc., a different company, and therefore its content is not applicable to SRRK.US. Articles
2
and
3
explicitly state an inability to access their content, meaning no information could be extracted from them.

No War, No Weapons

0

The provided articles do not contain any specific, concrete data points or evidence related to Scholar Rock Holding Corporation (SRRK.US) for any of the KPIs under the 'No War, No Weapons' ethical value. The articles discuss general defense industrial policy, export controls, and think tank funding, but none of this information is attributable to SRRK.US. The company description outlines its primary focus on developing medicines, but this does not constitute explicit evidence for any of the quantitative or policy-based KPIs in the rubric. Therefore, no KPIs can be scored based on the evidence provided.

Planet-Friendly Business

0

The provided article from MarketBeat.com offers a sustainability summary for Scholar Rock, including a "Net Impact Ratio" of 66.0% and various impact category scores.

1
However, the article explicitly states that it lacks specific metrics relevant to planet-friendly business and that the data presented is not directly comparable to standard sustainability reporting frameworks.
2
Consequently, no specific, quantitative data points required by the rubric's KPIs (such as emissions, renewable energy percentage, water usage, or waste diversion rates) are available to assess the company against the 'Planet-Friendly Business' value.
3

Respect for Cultures & Communities

0

No specific, concrete data points or policies related to the 'Respect for Cultures & Communities' value were found in the provided articles. The articles primarily consist of job postings, career page summaries, and a social media post about a company event, none of which contain information relevant to the defined KPIs.

1

Safe & Smart Tech

0

The company's privacy policy outlines user rights to access, correct, and delete data, and provides mechanisms to opt-out of marketing communications.

1
The policy states that data retention is based on necessity and legal requirements.
2
Additionally, the privacy policy indicates compliance with applicable data protection laws and regulations.
3

Zero Waste & Sustainable Products

0

No evidence available to assess Scholar Rock Holding Corporation on Zero Waste & Sustainable Products.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.