MASHINIi

Tharimmune, Inc..

THAR.US | Research and experimental development on natural sciences and engineering

Tharimmune, Inc. is a clinical-stage biotechnology company focused on the discovery and development of novel therapeutic candidates. The company's primary focus is on developing therapies for unmet medical needs, particularly in areas such as inflammation, immunology, and oncology. Tharimmune utiliz...Show More

Ethical Profile

Mixed.

Tharimmune, Inc. focuses on developing therapies for rare and inflammatory conditions, with its lead candidate TH104 showing promising tolerability in Phase 1 trials. The company secured $13.02 million in recent placements to advance clinical development, including a Phase 2 study planned for 2024, targeting vulnerable populations like those with PBC. However, Tharimmune received a Nasdaq non-compliance notice for allegedly failing to meet a $2.5 million stockholders' equity requirement, reporting $1.3 million. While the company's R&D inherently relies on animal testing, specific animal welfare practices are not detailed. Many other ethical areas, including fair pay, environmental impact, and supply chain ethics, lack sufficient public data for a comprehensive assessment.

Value Scores

Better Health for All-10
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals0
-100100
No War, No Weapons-40
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech-20
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

-10

Tharimmune's entire product pipeline is dedicated to developing therapeutic candidates for unmet medical needs, including treatments for chronic pruritus in primary biliary cholangitis (PBC), autoimmune diseases, and cancer, as well as prophylaxis for opioid overdose.

1
Phase 1 clinical trials for TH104 reported only mild adverse events, with no serious adverse events, and a comparable safety profile to intravenous nalmefene.
2
The company's products target vulnerable populations such as PBC patients (an orphan disease affecting 178,000 in the US, with 75% experiencing pruritus)
3
and high-risk individuals like military personnel and first responders exposed to potent opioids.
4
However, the company's forward-looking statements are subject to risks detailed in SEC filings,
5
and the dual focus on biotech and blockchain presents regulatory and investor challenges.
6
Tharimmune raised approximately $13 million in the last 12 months for clinical trials
7
and secured over $540 million in private placements,
8
indicating investment in innovation. The development of TH104 for opioid overdose prophylaxis addresses a significant public health crisis.
9
The company's operations are not explicitly linked to negative health externalities, but the article mentions the opioid crisis as a context for TH104's development.
10
Clinical trials are conducted under GCP regulations, requiring informed consent and IRB review,
11
with a Phase 1 study involving 20 healthy volunteers.
12

Fair Money & Economic Opportunity

0

Tharimmune, Inc. is a clinical-stage biotechnology company focused on developing therapeutic candidates.

1
The provided articles detail its financial offerings, regulatory filings, and product development, but do not contain any information related to financial services, lending practices, customer demographics, or community finance initiatives. As such, the company does not offer lending or deposit services to consumers, nor does it provide consumer credit products or manage customer finance data. Therefore, all KPIs under the 'Fair Money & Economic Opportunity' value are not applicable to Tharimmune's core business or reported activities.

Fair Pay & Worker Respect

0

No specific, concrete data points were found in the provided articles for any of the KPIs related to Fair Pay & Worker Respect. While executive compensation figures are mentioned (e.g., CEO total compensation of $791.16K in 2025),

1
there is no data on median employee compensation, which is necessary to calculate the CEO to median pay ratio.
2
Information regarding living wage coverage, collective bargaining share, safety incident rate, pay equity ratio, worker engagement score, turnover rate, labor violation incidents, insecure contract share, or health insurance coverage for the general workforce is not available.
3
The articles primarily focus on executive compensation, financial performance, and Nasdaq compliance issues, which do not provide the necessary metrics for this assessment.

Fair Trade & Ethical Sourcing

0

No evidence available to assess Tharimmune, Inc. on Fair Trade & Ethical Sourcing.

Honest & Fair Business

0

No specific, concrete data points were found in the provided articles to assess Tharimmune, Inc. against any of the 'Honest & Fair Business' KPIs. Information regarding regulatory fines, transparency benchmarks, whistleblower policies, financial restatements, audit coverage, ESG controversy scores, complaint resolution times, board conflict percentages, anti-corruption policies, or third-party verification of ethical claims was not available.

1
While a Nasdaq non-compliance notice was issued for failing to meet stockholders' equity requirements,
2
this was not identified as an ethics-related regulatory fine. Additionally, a statement of 'no known material legal proceedings' was present,
3
but it did not provide specific details on ethics-related fines or their value.

Kind to Animals

0

No evidence available to assess Tharimmune, Inc. on Kind to Animals.

No War, No Weapons

-40

Tharimmune, Inc. is developing TH104, a potential prophylactic treatment for opioid exposure, explicitly targeting both military personnel and first responders.

1
The company has appointed James Gordon Liddy, a retired US Navy SEAL with a background in counterterrorism and national security, as a strategic advisor.
2
The Department of Defense is noted to be procuring similar opioid prophylaxis countermeasures, indicating a market for such products for military use.
3
This suggests that the company's R&D investment is split between civilian and military applications for this dual-use technology.

Planet-Friendly Business

0

No specific, concrete data points were found across the provided articles for any of the Planet-Friendly Business KPIs. The articles primarily consist of an Executive Committee Charter, a press release about certifications for a different company's product, and 10-K filing information that does not detail environmental performance. Sustainability data is explicitly stated as unavailable or not provided in multiple sources, meaning no evidence could be extracted to score any KPI.

1

Respect for Cultures & Communities

0

No evidence available to assess Tharimmune, Inc. on Respect for Cultures & Communities.

Safe & Smart Tech

-20

Tharimmune's privacy policy, last revised in June 2023, allows users to opt out of marketing emails and control cookies via browser settings, which represents industry-standard user privacy controls.

1
The company's Board of Directors oversees management's processes for identifying and mitigating cybersecurity risks and is apprised of incidents with moderate or higher business impact.
2
Tharimmune engages third-party services to conduct evaluations of security controls through penetration testing and independent audits.
3
The company has a vulnerability disclosure program with a good scope and reasonable response times of 7-15 days. It also conducts regular security testing for 40-55% of its systems, with a comprehensive methodology for critical systems. Tharimmune must comply with regulations, including FDA requirements for safeguarding patient information and SEC reporting for cybersecurity incidents, and states it shares information to comply with the law.
4

Zero Waste & Sustainable Products

0

No evidence available to assess Tharimmune, Inc. on Zero Waste & Sustainable Products.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.