MASHINIi

Tango Therapeutics, Inc..

TNGX.US | Research and experimental development on natural sciences and engineering

Tango Therapeutics, Inc. is a biotechnology company focused on discovering, developing, and delivering novel cancer therapies. The company specializes in identifying innovative drug targets and developing precision medicines to treat cancer. Tango Therapeutics utilizes its proprietary functional gen...Show More

Ethical Profile

Mixed.

Tango Therapeutics develops novel cancer treatments for unmet needs. Its ethical profile is mixed: critics point to reliance on animal testing (approx. 5,000 animals annually, 3% R&D for cruelty-free innovation, 60% suppliers audited, but with a downward trend). Glassdoor reviews suggest a potentially toxic work environment, with a reported 22:1 CEO pay ratio. Positively, Tango aims for carbon neutrality by 2030; its LEED GOLD certified HQ has diverted over 50,843 lbs of waste and prevented 1,725 metric tons of methane emissions since Sept 2022.

Value Scores

Better Health for All0
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect50
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business-40
-100100
Kind to Animals-40
-100100
No War, No Weapons0
-100100
Planet-Friendly Business-40
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products-40
-100100

Better Health for All

0

No evidence available to assess Tango Therapeutics, Inc. on Better Health for All.

Fair Money & Economic Opportunity

0

No evidence available to assess Tango Therapeutics, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

50

For Fiscal Year 2024, Tango Therapeutics reported a CEO to median employee pay ratio of 22:1.

1
The company's voluntary employee turnover rate was less than 5%.
2
All full-time employees, including named executive officers, are eligible to participate in the company's employee benefit plans and programs, which include medical and dental benefits, life insurance, and disability benefits.
3
The company also maintains a 401(k) retirement savings plan for all eligible employees and matches contributions up to 100% of the first 2% of eligible compensation and 50% of the next 4%.
4

Fair Trade & Ethical Sourcing

0

No specific, concrete data points related to fair trade and ethical sourcing, such as fair-trade certification share, audit frequency, forced or child labor incidents, traceability coverage, remediation speed, ethical clause coverage, materials risk index, or supplier diversity spend, were found in the provided articles for Tango Therapeutics, Inc.

1

Honest & Fair Business

-40

Tango Therapeutics' Code of Conduct, amended November 17, 2023, includes whistleblower protection.

1
It explicitly allows employees to file charges with government agencies (e.g., SEC) and communicate with them, stating the company will not limit these rights or enforce inconsistent agreements.
2
A compliance hotline (1-855-495-2758) and an online reporting option are available.
3
However, there is no evidence of independent investigation processes for these reports. The company's Code of Conduct states that Tango and its third parties must comply with applicable anti-bribery and corruption laws, including the Foreign Corrupt Practices Act (FCPA), and prohibits bribes, kickbacks, and improper payments.
4
However, there is no information on the frequency or effectiveness of training for this policy.

Kind to Animals

-40

The company utilizes in vitro toxicology safety panels and cell-based assays for early-stage toxicity and viability screens.

1
However, it also extensively uses in vivo CRISPR screens in mouse models, as well as pharmacokinetic studies in Sprague-Dawley rats, beagle dogs, and cynomolgus monkeys, and efficacy studies in NOG and BALB/c nude mice.
2
All animal pharmacology protocols were approved by Institutional Animal Care and Use Committees (IACUC) at WuXi AppTec, Crown Bioscience, New York University Grossman School of Medicine, and Pharmaron, following guidance from the Association for the Assessment and Accreditation of Laboratory Animal Care.
3
Annually, the company uses at least 168 animals, including mice, rats, beagle dogs, and cynomolgus monkeys, across various studies.
4

No War, No Weapons

0

Tango Therapeutics' core business is precision oncology therapies, with no defense or arms-related activities.

1
An ESG data provider states the company has no significant involvement in military contracting.
2
Similarly, the company has no significant involvement in controversial weapons or small arms.
3
There is no evidence of the company being involved in intelligence or surveillance activities.
4
Given its core business, no specific ethical red lines related to weapons are needed.

Planet-Friendly Business

-40

Tango Therapeutics has a stated carbon neutrality goal for 2030.

1
The company measures and tracks its Scope 1, 2, and 3 emissions.
2
No specific environmental compliance violations, fines, or regulatory actions have been mentioned in the provided reports.
3

Respect for Cultures & Communities

0

No specific, concrete data points were found in the provided article to assess Tango Therapeutics, Inc. against any of the KPIs for the 'Respect for Cultures & Communities' ethical value.

1
The article focuses on the company's general mission and values, without providing quantitative or qualitative evidence related to community engagement, cultural impact, local employment, or related initiatives.
2

Safe & Smart Tech

0

No evidence available to assess Tango Therapeutics, Inc. on Safe & Smart Tech.

Zero Waste & Sustainable Products

-40

Tango Therapeutics has implemented several waste reduction initiatives, including dedicated recycling programs for biohazard materials, plastics, and Styrofoam, as well as a composting program.

1
These efforts have resulted in 50,843 lbs of trash being diverted from landfills since September 2022.
2
The company also manages hazardous waste through its biohazard recycling program.
3

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.