MASHINIi

Entrada Therapeutics, Inc..

TRDA.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Entrada Therapeutics, Inc. is a biopharmaceutical company focused on developing and advancing intracellularly acting therapeutics to treat diseases that have been historically undruggable. The company's proprietary Endosomal Escape Vehicle (EEV) platform is designed to enhance the intracellular deli...Show More

Ethical Profile

Mixed.

Entrada Therapeutics, Inc. (TRDA.US) presents a mixed ethical profile. The company's core mission is highly positive, focusing on developing therapies for debilitating neuromuscular diseases like Duchenne muscular dystrophy and myotonic dystrophy type 1, addressing significant unmet medical needs. However, reports indicate Entrada Therapeutics uses animals for pre-clinical studies, including for ENTR-501. There is no public data on the extent of this testing or any efforts to reduce or replace animal use, despite FDA encouragement for alternative methods that could spare thousands of animals annually. Critics also point to potential tensions between intellectual property protection and drug affordability or access. The company's integrity in clinical trial data and ethical research are paramount for its business.

Value Scores

Better Health for All-30
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals-70
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech-40
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

-30

Entrada Therapeutics' core mission is to develop intracellular therapeutics for devastating diseases like Duchenne muscular dystrophy, retinal, neuromuscular, and metabolic diseases, indicating that its entire business is devoted to health improvement with products intended to deliver exceptional health benefits.

1
There is no evidence of products with negative health impacts. The company demonstrates a strong commitment to health innovation, with its proprietary EEV™ Platform and RNA-based therapeutics focused on previously undruggable targets, representing 100% of its R&D and capital allocation.
2
The Entrada DREAMS grant program, launched in 2023, funds efforts to better identify, understand, and reach underrepresented and underserved individuals within the Duchenne muscular dystrophy community.
3
In 2025, this program awarded $50,000 USD to each of two non-profit organizations (one U.S.-based, one in the UK or EU).
4
The company offers employee benefits such as an Employee Assistance Program, Financial Coaching, Education Reimbursement, and Mental Wellness access.
5
It also provides a $500 Wellness Account, free drinks and snacks, and 100% coverage for preventative dental care.
6
The company offers education reimbursement to employees.
7
For clinical trials, Entrada states it will ask patients and families to identify potential obstacles to participation.
8

Fair Money & Economic Opportunity

0

No evidence available to assess Entrada Therapeutics, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

No evidence available to assess Entrada Therapeutics, Inc. on Fair Pay & Worker Respect.

Fair Trade & Ethical Sourcing

0

No information regarding fair trade and ethical sourcing practices, supplier audits, labor incidents, supply chain traceability, remediation speed, ethical clauses in contracts, high-risk materials, or supplier diversity spend for Entrada Therapeutics, Inc. was found in the provided article.

1

Honest & Fair Business

0

No specific, quantifiable evidence was found in the provided article to score any of the KPIs according to the rubric's quantitative thresholds. The article mentions a lawsuit alleging Entrada Therapeutics Inc. failed to disclose key documents and underpaid $20 million in sublicensing fees, a finding made by an independent royalty examiner.

1
However, this information does not directly map to the required metrics for regulatory fines, transparency index, controversy scores, or the extent of third-party verification as defined by the rubric's scoring tiers, which often require specific percentages or index scores.

Kind to Animals

-70

Entrada Therapeutics, Inc.'s policy is to use animals for pre-clinical studies, with specific examples including animal studies with ENTR-501.

1
The company does not participate in any formal collaborations related to animal-free R&D or engage with animal welfare stakeholders.
2
There is no public position on animal welfare legislation or engagement with industry standards.
3

No War, No Weapons

0

No evidence available to assess Entrada Therapeutics, Inc. on No War, No Weapons.

Planet-Friendly Business

0

The provided article focuses on company appointments, regulatory approvals, and clinical trials, and does not contain any data relevant to planet-friendly business metrics, environmental impact, or sustainability.

1
Therefore, no evidence could be extracted to score any of the KPIs.

Respect for Cultures & Communities

0

No specific, concrete evidence was found in the provided article to assess TRDA.US against any of the KPIs for the 'Respect for Cultures & Communities' ethical value.

1
The provided article URL led to a Google search page, which contained no relevant data.
2

Safe & Smart Tech

-40

Entrada Therapeutics allows users to request access, update, correct, or delete their personal information by contacting privacy@entradatx.com, and users can withdraw consent for processing.

1
However, the right to deletion is noted as not absolute.
2
The company warns about fraudulent hiring practices, stating they will never initiate contact via text or messaging apps, nor request sensitive financial information, and only use the @entradatx.com domain for legitimate business emails.
3
The company collects personal information for various business activities, including recruitment, product development, and marketing, and processes sensitive personal information only with express consent or as required by applicable law.
4
The privacy notice states that the site is not directed to children under 18.
5
The company implements commercially reasonable technical, administrative, and organizational measures to protect personal information and mentions using Google Analytics to collect and analyze website use.
6

Zero Waste & Sustainable Products

0

No information was found regarding Entrada Therapeutics, Inc.'s performance on waste management, product sustainability, or circular economy practices.

1
The provided article focuses on the company's clinical studies and therapeutic development, offering no data relevant to waste diversion, product recyclability, packaging, or other related KPIs.
2

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.