Entera Bio Ltd..
ENTX.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products
Entera Bio Ltd. is a clinical-stage biopharmaceutical company focused on the development and commercialization of orally delivered large molecule therapeutics for unmet medical needs. The company's lead product candidate is EB613, an oral formulation of human parathyroid hormone (PTH) for the treatm...Show More
Better Health for All
10
Entera Bio is a clinical-stage biopharmaceutical company focused on developing oral therapies for unmet medical needs
1
, including osteoporosis, hypoparathyroidism, obesity, and malabsorption conditions.
2
Its entire business is devoted to health improvement, with product candidates aiming to provide exceptional health benefits. Phase 2 studies for EB613 (osteoporosis) showed statistically significant increases in bone mineral density (BMD) and bone formation markers, with results comparable to or exceeding injectable alternatives.
3
Similarly, Phase 2a studies for EB612 (hypoparathyroidism) demonstrated a 42% decrease in supplemental calcium usage and a 5% increase in quality of life.
4
The company has no revenue from products with negative health impacts. Both EB613 and EB612 clinical trials reported no drug-related serious adverse events, with common adverse events being mild and well-tolerated.
5
The company's research and development expenses were $1,123,000 in Q1 2025, representing 100% of its operating expenses dedicated to innovation.
6
Clinical trials for EB613 were approved by institutional review boards (IRBs) and the Israeli Ministry of Health.
7
However, for EB613, an oral version of teriparatide, the article notes that the patent has expired, which suggests a lack of proactive patent flexibility for its own intellectual property, placing it in a lower tier for this KPI.
8
Fair Money & Economic Opportunity
0
No evidence available to assess Entera Bio Ltd. on Fair Money & Economic Opportunity.
Fair Pay & Worker Respect
0
Entera Bio Ltd. (ENTX.US) reported having no material legal proceedings as of December 31, 2023.
1
The company has a small workforce, with 19 employees (17 full-time, 1 part-time consultant) in Israel, plus advisors in the US, UK, and Europe.
2
No specific data on health insurance coverage for ENTX.US employees was provided.
Fair Trade & Ethical Sourcing
0
No information regarding Entera Bio Ltd.'s fair trade certifications, supplier audit frequency, forced or child labor incidents, supply chain traceability, remediation speed for violations, ethical clause coverage in supplier contracts, spend on high-risk materials, or supplier diversity spend was found in the provided articles.
1
Honest & Fair Business
0
No evidence available to assess Entera Bio Ltd. on Honest & Fair Business.
Kind to Animals
-50
Entera Bio Ltd. conducts animal testing for medical analysis and clinical research, as stated on their website, leading to its inclusion on a cruelty-free investing list for exploiting animals.
1
The company's policy is not explicitly stated, but its practice of animal testing for preclinical studies, including the use of mini-pigs for validation and PK/PD data, indicates a policy that permits such testing.
2
The company uses both *in vitro* and *in vivo* methods for validation of PTH analogs, suggesting that while non-animal assays may be used, animal tests are still employed for complex endpoints.
3
No War, No Weapons
0
Entera Bio Ltd. (ENTX) is a biopharmaceutical company focused on oral peptide and protein therapies.
1
The company is explicitly stated as not being a defense contractor, not involved in peacebuilding, and not using AI in its operations.
2
Therefore, all KPIs related to arms, defense, dual-use technology, military sales, conflict-zone activities, or peacebuilding initiatives are noted as 'Not applicable' to its core business.
3
Planet-Friendly Business
-20
The company sources 28% of its operational energy consumption from renewables.
1
It diverts 55% of its waste from landfill through reuse, recycling, or recovery.
2
The company has achieved a 35% reduction in packaging CO2 per unit.
3
Respect for Cultures & Communities
0
No evidence available to assess Entera Bio Ltd. on Respect for Cultures & Communities.
Safe & Smart Tech
0
No evidence available to assess Entera Bio Ltd. on Safe & Smart Tech.
Zero Waste & Sustainable Products
0
No evidence available to assess Entera Bio Ltd. on Zero Waste & Sustainable Products.