Senti Biosciences, Inc..
SNTI.US | Research and experimental development on natural sciences and engineering
Senti Biosciences, Inc. is a biotechnology company focused on developing gene circuits for cell and gene therapies. These gene circuits are designed to program cells with biological logic to sense inputs, compute decisions, and respond to their cellular environment. The company's technology platform...Show More
Better Health for All
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Senti Biosciences is developing cell and gene therapies, such as SENTI-202, designed to fight challenging diseases like relapsed or refractory Acute Myeloid Leukemia (AML) by selectively killing cancer cells while sparing healthy ones.
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The company's entire business is devoted to health improvement, with its pipeline targeting liquid and solid tumors.
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SENTI-202 has received FDA Regenerative Medicine Advanced Therapy (RMAT) and Orphan Drug designations.
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Clinical data for SENTI-202 showed deep and durable complete remission rates combined with a well-tolerated safety profile, with no dose-limiting toxicities or SENTI-202-related serious adverse events.
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The company is currently enrolling adult patients with R/R CD33 and/or FLT3 expressing heme malignancies in a Phase 1 clinical trial for SENTI-202, with responses observed in patients with multiple poor prognostic indicators.
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The company's prospectus includes a 'Risk Factors' section detailing potential safety risks associated with its gene circuit platform technologies.
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The company is subject to U.S. and international data protection laws, including HIPAA and GDPR, and its prospectus mentions the risk of security or data privacy breaches.
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Senti Bio is a clinical-stage biotechnology company leveraging a synthetic biology platform to engineer Gene Circuits for next-generation cell and gene therapies.
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The company is conducting a multinational, multicenter dose-finding study for SENTI-202, which is registered on clinicaltrials.gov (NCT06325748), and is required to comply with GCP standards and obtain IRB approval.
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Fair Money & Economic Opportunity
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Senti Biosciences, Inc. is a biotechnology company focused on developing gene circuits for cell and gene therapies.
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The provided articles detail its financial performance, clinical trial progress, and financing activities. There is no evidence in any of the articles to suggest that the company offers lending, insurance, or other financial services to consumers. Therefore, all KPIs under the 'Fair Money & Economic Opportunity' value are not applicable to Senti Biosciences' core business model.
Fair Pay & Worker Respect
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Senti Biosciences reports that 0% of its employees are covered by collective bargaining agreements as of February 16, 2023.
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The company provides comprehensive health insurance coverage for 100% of its employees, along with a 401(k) plan with instant vesting options and paid time off during the winter holiday season.
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Fair Trade & Ethical Sourcing
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No evidence was found in the provided articles to assess SNTI.US against any of the KPIs for Fair Trade & Ethical Sourcing. The articles primarily contain financial information, corporate governance details, and product development timelines, with no specific data points regarding fair trade certifications, supply chain audits, labor incidents, traceability, remediation, ethical clauses in supplier contracts, materials risk, or supplier diversity spend.
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Honest & Fair Business
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Senti Biosciences is currently under investigation by Pomerantz LLP for potential securities fraud, announced on April 28, 2025.
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This investigation followed the halting of enrollment in an Investigator Sponsored Trial for SN301A due to dose-limiting toxicities, which resulted in a 27.2% drop in the company's stock price.
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Additionally, the company's gross proceeds from its business combination, approximately $140.3 million to $140.7 million, fell short of the anticipated minimum cash condition of approximately $151.7 million.
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Kind to Animals
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No evidence available to assess Senti Biosciences, Inc. on Kind to Animals.
No War, No Weapons
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Senti Biosciences, Inc. is a biotechnology company focused on developing gene circuits for cell and gene therapies to fight challenging diseases.
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Their gene circuit platform technologies are designed for applications in various cell types and in vivo gene therapy.
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There is no evidence to suggest that the company develops or sells dual-use products with military applications.
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Planet-Friendly Business
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No evidence available to assess Senti Biosciences, Inc. on Planet-Friendly Business.
Respect for Cultures & Communities
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No evidence available to assess Senti Biosciences, Inc. on Respect for Cultures & Communities.
Safe & Smart Tech
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No evidence available to assess Senti Biosciences, Inc. on Safe & Smart Tech.
Zero Waste & Sustainable Products
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The provided articles do not contain specific, concrete data points for any of the KPIs related to Zero Waste & Sustainable Products for Senti Biosciences, Inc. There is no information available regarding waste diversion rates, product recyclability, packaging sustainability, recycled content, single-use plastic reduction, take-back programs, circular design principles, waste reduction initiatives, hazardous waste management, product durability, repairability, waste audit frequency, zero waste certification, waste disposal violations, material efficiency, packaging-to-product ratio, waste reduction targets, supplier waste requirements, or customer waste education.
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While one article mentions Senti Biosciences leased a property for a manufacturing facility,
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any certifications or sustainable practices mentioned in that article refer to other, unrelated properties or projects, not Senti Biosciences' operations or facilities.