MASHINIi

Tourmaline Bio, Inc..

TRML.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Tourmaline Bio, Inc. is a clinical-stage biotechnology company focused on developing transformative medicines to benefit patients with debilitating diseases. Their lead product candidate, TOUR006, is a fully human anti-IL-6 antibody being developed for the treatment of Thyroid Eye Disease (TED) and ...Show More

Ethical Profile

Mixed.

Tourmaline Bio, Inc. (TRML.US) has a mixed ethical profile. The company is actively developing TOUR006 for serious conditions like atherosclerotic cardiovascular disease, with Phase 2 trials showing statistically significant reductions in cardiovascular risk indicators. Their commitment to health innovation is evident through trials involving 448 participants, conducted using ethical, double-blind, placebo-controlled methods. However, an expanded access program for TOUR006 is currently unavailable, and the long-term accessibility and pricing of the drug are not yet clear. Critics also point to the inherent reliance on animal testing in preclinical drug development, a standard practice in the biotech industry that conflicts with animal welfare values.

Value Scores

Better Health for All40
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals0
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

40

Tourmaline Bio is a clinical-stage biotechnology company entirely focused on developing transformative medicines for debilitating diseases. Its lead product candidate, pacibekitug (TOUR006), demonstrated statistically significant, rapid, and durable reductions in high-sensitivity C-reactive protein (hs-CRP) levels, with over 85% reduction in one treatment arm during a Phase 2 trial.

1
The company's entire R&D and capital allocation is dedicated to developing these health-improving medicines, as evidenced by its ongoing Phase 2 TRANQUILITY trial and six prior Phase 1 and 2 trials involving 448 participants.
2
The TRANQUILITY study is designed as a randomized, double-blind, and placebo-controlled trial, which reflects strong ethical standards in clinical research.
3

Fair Money & Economic Opportunity

0

The provided articles explicitly state that no data relevant to Tourmaline Bio, Inc. or the 'Fair Money & Economic Opportunity' value is present.

1
The company's core business, as described, is biotechnology, not financial services.
2
Therefore, no specific, concrete data points could be extracted from the evidence to score any of the KPIs in this category.

Fair Pay & Worker Respect

0

No evidence available to assess Tourmaline Bio, Inc. on Fair Pay & Worker Respect.

Fair Trade & Ethical Sourcing

0

No evidence available to assess Tourmaline Bio, Inc. on Fair Trade & Ethical Sourcing.

Honest & Fair Business

0

No evidence available to assess Tourmaline Bio, Inc. on Honest & Fair Business.

Kind to Animals

0

No evidence available to assess Tourmaline Bio, Inc. on Kind to Animals.

No War, No Weapons

0

No evidence available to assess Tourmaline Bio, Inc. on No War, No Weapons.

Planet-Friendly Business

0

No data is available in the provided articles to assess Tourmaline Bio, Inc. against any of the Planet-Friendly Business metrics.

1
Both articles explicitly state that no quantitative data or ESG metrics relevant to planet-friendly business practices were found.

Respect for Cultures & Communities

0

No specific, quantitative evidence was found in the provided articles for any of the KPIs related to 'Respect for Cultures & Communities'. The articles primarily discuss financial results, clinical trials, or general ESG risk ratings without providing data on formal partnerships, community reinvestment, cultural incidents, impact assessments, local employment, grievance mechanisms, or other community-related metrics.

1

Safe & Smart Tech

0

No evidence available to assess Tourmaline Bio, Inc. on Safe & Smart Tech.

Zero Waste & Sustainable Products

0

The provided article for Tourmaline Bio, Inc. does not contain any quantitative data or specific details relevant to waste management, product recyclability, packaging sustainability, or other metrics for the Zero Waste & Sustainable Products value.

1

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.