MASHINIi

Third Harmonic Bio, Inc..

THRD.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Third Harmonic Bio, Inc. is a clinical-stage biopharmaceutical company focused on developing a highly selective, oral KIT inhibitor for the treatment of severe allergic diseases. Their lead product candidate is THB002, which is being developed for chronic urticaria and other mast cell-mediated disea...Show More

Ethical Profile

Mixed.

Third Harmonic Bio, Inc. is currently in the process of dissolving, having received an overall "Mixed" ethical rating. As a biopharmaceutical company, its operations inherently conflict with being "Kind to Animals" due to reliance on animal testing for drug development. While focused on "Better Health for All" through novel treatments like THB335 for inflammatory diseases, the accessibility and affordability of future products remain unknown. Reports suggest a High ESG risk rating of 34.1 from Sustainalytics, though specific environmental data is limited. The company maintains a cybersecurity program, but comprehensive information on fair pay, ethical sourcing, and honest business practices is largely insufficient.

Value Scores

Better Health for All0
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business-40
-100100
Kind to Animals0
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

0

No evidence available to assess Third Harmonic Bio, Inc. on Better Health for All.

Fair Money & Economic Opportunity

0

No evidence available to assess Third Harmonic Bio, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

The provided articles do not contain specific, quantitative data points for any of the KPIs under the 'Fair Pay & Worker Respect' value. There is no evidence regarding living wage coverage, CEO to median pay ratio (as median employee pay is not disclosed), collective bargaining share, safety incident rates, pay equity ratio, worker engagement scores, or insecure contract share.

1
While articles mention the company laid off 50% of its workforce in February 2025,
2
this is an involuntary separation and does not constitute voluntary employee turnover as defined by the 'turnover_rate' KPI. Similarly, although the company's career information mentions offering benefits like medical, dental, and vision,
3
it does not provide the percentage of the workforce covered, which is required for the 'health_insurance_coverage' KPI. The mention of a recruitment fraud warning is not a substantiated labor-law violation by the company,
4
thus no data for 'labor_violation_incidents' is available.

Fair Trade & Ethical Sourcing

0

No direct evidence was found in the provided articles for any of the Key Performance Indicators related to Fair Trade & Ethical Sourcing. The articles primarily discuss the company's financial results, clinical trial progress, and licensing agreements, without detailing information on fair trade certifications, supply chain audits, forced or child labor incidents, supply chain traceability, remediation processes, ethical clauses in supplier contracts, materials risk, or supplier diversity spend. A general mention of compliance with 'Applicable Law' in one article is not specific enough to score any KPI.

1

Honest & Fair Business

-40

The company provides a link to a whistleblower hotline.

1
However, there is no evidence provided regarding the existence of a formal policy, independent investigation processes, training, or other details about the program's effectiveness or scope.

Kind to Animals

0

No information relevant to the 'Kind to Animals' value or any of its associated KPIs was found in the provided articles.

1
The articles either explicitly state a lack of relevant data or were inaccessible.
2

No War, No Weapons

0

No evidence available to assess Third Harmonic Bio, Inc. on No War, No Weapons.

Planet-Friendly Business

0

The provided articles do not contain any specific, concrete data points or facts related to the company's environmental performance. There is no information regarding greenhouse gas emissions, renewable energy usage, water consumption, waste diversion rates, climate targets, or environmental compliance.

1
Details on initiatives for biodiversity, climate justice, or supply chain transparency are also absent.
2
The articles primarily focus on the company's financial status, liquidation plans, and corporate governance details, which do not provide evidence for the 'Planet-Friendly Business' KPIs.

Respect for Cultures & Communities

0

The provided articles focus on Third Harmonic Bio's plan of liquidation and dissolution, financial distributions to stockholders, and updated Phase 1 clinical trial data for its drug candidate, THB335.

1
No information or specific data points related to the company's engagement with local or indigenous communities, cultural impact assessments, cultural preservation efforts, local employment, procurement, or any other metrics pertaining to 'Respect for Cultures & Communities' were found in the evidence.
2

Safe & Smart Tech

0

No specific, quantifiable evidence was found in the provided articles to assess the company against any of the 'Safe & Smart Tech' KPIs. While Article 0 mentions the existence of a cybersecurity program, assessments, training, incident response, identity and access management, patch management, threat hunting, and security testing, it does not provide the specific metrics, percentages, or outcomes required by the rubric for scoring.

1
Similarly, the mention of being subject to regulations like HIPAA, GDPR, and CCPA does not provide evidence of the company's compliance effectiveness or any related incidents.
2

Zero Waste & Sustainable Products

0

No specific, quantitative data related to Third Harmonic Bio, Inc.'s waste management, product design, or sustainability practices for any of the 'Zero Waste & Sustainable Products' KPIs was found in the provided articles.

1
The articles primarily discuss the company's plans for liquidation and dissolution, financial details, and general industry trends in pharmaceutical sustainability, without offering company-specific metrics.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.